In 2011, the U.S. Food and Drug Administration approved a drug that can help prevent deep vein thrombosis, the term used to describe blood clots that occur in a deep vein most typical in patients that have undergone hip replacement surgery. Over the next several years, the FDA began to approve Xarelto for other uses, as well. Today, the drug is generally used as a way to lower risks of blood clotting caused by cardiovascular issues and other medical conditions.
Xarelto is among the latest generation of anticoagulant drugs prescribed to patients facing increased risks of abnormal blood clotting. The drug, which is also referred to by its active ingredient rivaroxaban, works by regulating the production of the proteins that causes blood to clot. For healthy individuals, these proteins help prevent open wounds from bleeding out. However, for someone facing complications due to certain medical conditions, a blood clot can be particularly dangerous. Taking Xarelto and other similar medications have proven to be an effective way of mitigating such dangers. Unfortunately, there have been talks of particular side effects that may prove that Xarelto isn’t as safe as its manufacturers have once claimed it to be.
As noted on the website of Williams Kherkher Law, the FDA recently announced that the use of Xarelto should not be permitted for patients of acute coronary syndrome. This decision was due to the fact that the side effects caused by the drug are known to exacerbate particular symptoms of the condition. Even when a good number of patients find that Xarelto is an effective way to address their issues with abnormal clotting, special circumstances such as the one noted by the FDA can lead to more adverse side effects such as severe gastrointestinal bleeding.
While it may prove effective for some patients, taking Xarelto is also known to cause considerable harm to others. Patients would be able to avoid these harmful side effects if manufacturers are more upfront about their products.
Deep vein thrombosis occurs when blood clots form in veins, preventing blood flow and causing swelling and pain. This usually occurs in limbs, such as the arms and legs. These blood clots are a danger as they may unlatch and move towards the lungs, a medical condition known as a pulmonary embolism.
The condition is most common during the recovery process after surgery. Individuals are less likely to be physically active and may be bed ridden during this time, increasing the risk of blood clots because of lessened blood flow. To treat this risk, physicians prescribe anticoagulants such as Xarelto to thin the blood and encourage blood circulation.
The most common possible complications of deep vein thrombosis are pulmonary embolisms and postphlebitic syndrome. Potentially fatal pulmonary embolisms are caused when blood clots prevent blood flow to the lung. Symptoms include shortness of breath, chest pain, rapid pulse, and coughing up blood.
Postphlebitic syndrome is the more common side effect of deep vein thrombosis. This medical condition occurs when a blood clot damages veins around the affected area. Symptoms of this may include swelling of the legs, pain, skin discoloration, and skin soreness.
Xarelto, a popular blood thinner released by Johnson & Johnson and Bayer, was originally used to treat deep vein thrombosis in patients. According to the website of Williams Kherkher’s Xarelto lawyers, the drug was created to prevent blood clots after knee and hip surgeries. However, it was found that the use of Xarelto increases bleeding risks in its patients, leading to a number of serious injuries and fatalities.
If you or a loved one suffered damages due to Xarelto contact a personal injury lawyer in your area to discuss your legal options. You may be entitled to compensation for medical bills, lost wages, and other damages that the manufacturers of Xarelto caused.
As legend would have it, this family business led to Mrs. Sarah Winchester believing that by continuously constructing her mansion in eccentric ways, it would confuse the spirits that she so believed haunted her every move. Shocked after the trauma of losing her child and husband so quickly, she spent most of her inheritance into the building of this extravagant mansion that is the epitome of elegant yet incredibly intriguing Victorian era architecture. She followed the advice of a medium and resorted into having regular séances in order to know what changes to make and what further rooms to build. With no blueprints and no real tangible guide, this is a house that will never lack in peculiarities and surprises.
Now, there are tours available for guests to be escorted through 110 of the 160 rooms in order to see the many oddities that were installed in the house upon its relentlessly continued construction such as windows on the floor, doors and staircases that lead to nowhere, and other such curiosities. There are many unsolved mysteries that are woven with this great house and when touring the area, it is advisable that guests are encouraged not to stray from the tour. After all, this is not a mansion called a “house built by spirits” for nothing… and, as the place is quite enormous, it could be several hours before you are found!
Appease your senses, delight your curiosity, and see these wondrous things for yourself by entering this one of a kind house of mystery!
An unusual type of uncontested divorce is divorce by publication. Generally, this is an action that applies when one spouse is missing and cannot be located. In North Carolina, in order to file a divorce by publication, the petitioning spouse will have to convince a judge that his or her spouse cannot be located despite good faith efforts to find the missing spouse.
This is a type of divorce that is not encouraged by North Carolina courts, and is considered an action of last resort. The petitioning spouse will have to go through what is called a “diligent search” which includes but not limited to:
An Affidavit of Diligent Search will detail and attest to the fact that the petitioner had pursued all possible avenues to locate the respondent. When this has been complicated to the court’s satisfaction, the petitioner can then file a Divorce by Publication as described in North Caroline Rules of Civil Procedure.
This is initiated by a Notice of Service of Publication, which is typically published once a week for three weeks in the county where the divorce was filed. A copy of the notice is also sent to the last known postal address of the respondent, which is attested in an Affidavit of Service by Publication signed by an authorized representative of the publication. This gives the respondent 40 days to respond. No response within that period releases the court from any obligation to require the presence of the respondent in the divorce action, which is then considered uncontested. To know more about it, check http://marshalltaylorlawfirm.com/ and ask for an initial consultation.
Germany-based drug maker Bayer Corp. with US distributor Janssen Ortho LLC (a division of Johnson & Johnson) have stepped up efforts to further expand the number of medical conditions approved for the pair’s direct factor Xa (10-a) inhibitor drug Xarelto. This will mean a potentially broader market for the already frequently prescribed anticoagulant drug.
Xarelto was only approved by the Food and Drug Administration (FDA) for the American market in July 2011 but it rapidly overtook its predecessor Boehringer Ingelheim’s Pradaxa and continues to outpace latest entrant Eliquis from Pfizer and Bristol-Meyers Squibb. Xarelto is currently approved for more medical conditions than Pradaxa and Eliquis but the principals are seeking to press their advantage even more by getting approval for the drug for acute coronary syndrome (ACS) as well as peripheral artery disease and embolic stroke of undetermined source.
ACS alone accounts for an additional 1.1 million hospital admissions every year, which is why Bayer and J&J have tried three times to get Xarelto signed off for the medical condition but the FDA said no go. Apparently, the pair is not into baseball as they don’t consider three strikes and you’re out. They have come up with a whole set of new tests designed to convince the skeptical FDA advisory committee that Xarelto is perfectly safe for the treatment of ACS as well as peripheral artery disease and embolic stroke. According to the website of Williams Kherkher, however, studies indicate that Xarelto poses a significant danger of serious side effects to patients.
It is a bit of a puzzle why Bayer and J&J are aggressively pursuing this expansion when the first lawsuits are already docketed with state courts. When that ball gets rolling, the pair could be facing hundreds, if not thousands of litigants, especially if the recent ruling by the Pennsylvania Supreme Court expanding the liability well of drug companies to include selling drugs they knew to be dangerous begins being applied in other state courts.
But perhaps Bayer and J&J figure there’s more to gain in the next two years than it might lose in payouts and settlements. Xarelto is currently bringing in more than $800 million a year. If you have suffered serious injury from using the drug, contact a dangerous drugs lawyer immediately to find out your legal options.
Dealing with lawyers is something that nobody wants to contemplate, as it often implies problems or troubles that are somehow undesirable. But, by gaining a bit of education about lawyers and how to find a good one, the experience is not something you need to dread. By reviewing the following information, you will have the preparation you need.
Ask for a fee schedule from every attorney you are interviewing. Fees are going to differ quite a bit depending on that lawyer’s experience and demand. This means that you must know what the fees will be prior to paying them. You do not want to lose your lawyer after your matter has already proceeded because you lack the funds.
You may find that your friends, family, and coworkers can provide a wealth of information when it comes to finding a lawyer who can best fit your needs. Ask around and see what experiences people have had with particular lawyers, or if they have any advice for you based on their circumstances. Lots of the time, lawyers like the ones at www.abelinjurylawyers.com have this kind of information on their website.
If you notice that the lawyer you chose is not doing the job that you were expecting, do not be afraid to fire them. This is the person that you are paying your money for, so at any point you can cut ties. If you are facing a legal matter, you only want the best on your side.
A great tip if you’re thinking about hiring a lawyer is to make sure the lawyer you select answers all of the questions that you have. You don’t want to pick a lawyer who can’t give you a straight answer because you’ll be left in the dark and won’t know what’s going on.
There is no denying the fact that lawyers and the work they do can strike fear in the hearts of just about anyone. However, if you take the time to educate yourself about finding and working cooperatively with a lawyer, you stand to benefit a great deal. With any luck, the piece above has provided the information you needed.
If you have a sport utility vehicle (SUV) or light truck, you should be aware by now that you have a higher risk of getting involved in single-vehicle rollover accidents than someone in a sedan. Even non-fatal rollover accidents can change your life forever, and not in a good way. Even if you successfully sue for compensation for your medical and financial losses, it is still something you want to avoid. While regrets may come too late in the day and you’re stuck with an SUV or light truck, you can still avoid becoming a statistic by observing the following precautions.
Studies all agree that wearing a seatbelt is a significant factor on the survival rate of anyone involved in a vehicular accident, but most especially in rollover accidents. More than three-fourths of people who died in a rollover accident were not wearing one at the time of the crash.
A tire blowout because it is worn or over-inflated is one cause of rollovers. You can keep this from happening by simply checking to see if the tires are in reasonably good condition and checking the tire pressure periodically. In some cases, a defective tire may blow out for no reason, so check if your tires are among those being recalled for defects.
The risk of rollovers increases in SUVs and light trucks when it is loaded, so avoid overloading the vehicle. Load ratings are usually indicated in your vehicle’s owner’s manual, and it would be advisable to keep heavy loads as near to the middle of the vehicle as possible.
Many rollover accidents happen when driving beyond the speed limit or driving faster than conditions allow, and higher speeds usually result in more serious accidents. Keep a light foot on the accelerator and you should be fine.
Most rollover accidents are single-vehicle and occur on long stretches of rural roads, where the posted speed limit is at or in excess of 55 mph and there are no barriers. If you regularly travel in your SUV along rural roads, be cautious. You can find more information here about driving safely.